I am a lipid biochemist and Professor of Biochemistry at Cardiff University. Prior to this, I have been a Wellcome Trust Fellow (Cardiff), Parker B Francis Fellow (University of Alabama at Birmingham) and EU Marie Curie Fellow (University of Berne). The research of my group is focused on using mass spectrometry for discovery and characterization of lipids in inflammation, wound healing and thrombosis. We mainly focus on around molecular species of lipids termed enzymatically-oxidized phospholipids (eoxPL) made by platelets, neutrophils, monocytes and eosinophils. We showed that they are essential for normal blood clotting, and conversely are elevated in thrombotic disease. The detailed biochemical and biophysical mechanisms of action were elucidated. The lipids regulate neutrophil antibacterial actions and transcriptional activation in monocytes. They they are part of the healthy innate immune system, however when inappropriately generated in the blood stream or in excess, they contribute to vascular inflammation. Current studies are delineating the roles of eoxPL in vascular inflammation associated with aortic aneurysm, myocardial infarction and inflammatory diseases such as rheumatoid arthritis. Recently, we demonstrated a role for mitochondria in oxylipin metabolism during inflammation.